Included below are details regarding a small number of the more than 200 compounds which have been isolated from Kambo to date. These details should be seen as merely an introduction to the possible mechanisms of how Kambo may affect the physical form. There are no peer reviewed papers describing the work it allows us to do on higher dimensional planes. We encourage you to do your own research about the potential uses of Kambo.
Peptides are chains amino acids and some people may confuse peptides with proteins. Both proteins and peptides are made up of amino acids, but peptides contain far fewer amino acids than proteins. Peptides may be easier for the body to absorb than proteins because they are smaller and more broken down than proteins. They can more easily penetrate the skin and intestines, which helps them to enter the bloodstream more quickly.
These are the major bioactive peptides:
Caerulien– Ceruletide, also known as cerulein or caerulein, is a ten amino acid oligopeptide that stimulates smooth muscle and increases digestive secretions. Ceruletide stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle.
Sauvagine– Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands
Phyllomedusin– Phyllomedusin is a peptide of the tachykinin family. Phyllomedusin strongly affects the salivary glands, tear ducts, intestines, and bowels.
Phyllokinin – Hypothesized to produce relaxation of arterial smooth muscle and constriction of intestinal smooth muscle May target bradykinin receptors.
Dermorphin – The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu Opioid receptors. Dermorphin is about 30–40 times more potent than morphine. This mu Opioid affinity may account for the pain relief experienced by many Kambo recipients after their sessions.
Deltorphin – Deltorphin is a heptapeptide with a very potent opiate-like activity. Has high affinity and selectivity for delta-type opioid receptors. The two dermorphin-like peptides have a similar affinity and selectivity for the mu opioid receptor as dermorphin. Deltorphin is also a powerful painkiller and delta opioid agonist
Adenoregulin – Adenoregulin is a member of the dermaseptin family which are vertebrate antibiotic peptides having lethal effects against a broad spectrum of bacteria, fungi and protozoa.
Tryptophyllins – Highly potent against the yeast candida, may have potential in cardiovascular, inflammatory and anticancer therapy.
Dermaseptin – Induces potent antimicrobial activity against bacteria, yeast, fungi, protozoa, and enveloped viruses that often cause severe opportunistic infections.